Familiarity Breeds Contempt is an achievement/trophy in Dishonored 2.
How to Acquire
To unlock this achievement, Corvo Attano or Emily Kaldwin must steal the contents of the safe in Doctor Galvani's new home in the Tower District twice, once during the mission A Long Day in Dunwall and once during the mission Death to the Empress. His house is located near the street-level entrance to Dunwall Tower.