Santiago Fisheries is a major business in Karnaca, producing various canned seafood.
The Santiago Fisheries are located on the far western side of the Karnaca Bay, south from the Aventa Quarter. The fisheries have several docks for whaling trawlers to anchor before departing through the Grand Serkonan Canal, as well as three large pools for live catch.
- None of Santiago's products appear in Dishonored 2, despite the fisheries being mentioned in the game.
- Cans and bocals of Santiago seafood were conceptualized for Dishonored 2 but do not appear in the game.