- "Wyrmwood Way. Most in Dunwall know the name. Few ever come here, and with good reason--"
- —Cottings musing about Wyrmwood Way
This street is described as "a gathering place for fringe alchemists, bonecharm crafters, and the practitioners of every superstitious creed from every corner of the Empire". The Overseers are said to scour the place every few years, and once even burned half of it to the ground. Despite the tenacity of the Overseers, those who seek the services of such a place as Wyrmwood Way always manage to come back.
Martha Cottings' investigation into contraband weapons leads the Watch Officer twice to Wyrmwood Way in search of a clue on the supplier to the city's criminal gangs. Her steps leads her to the shop of Titus Grindle and later to the witch behind the plot.
- Though its exact location is not mentioned, Wyrmwood Way seems to be on the same side of the Wrenhaven River as the Distillery District.